Decoding IPEX Syndrome: From FOXP3 Mutation to Immunodysregulation

IPEX syndrome is a rare genetic disorder caused by mutations in the FOXP3 gene, crucial for regulatory T cell function. Symptoms include enteropathy, endocrinopathy, and dermatitis, appearing early in life. Management involves immunosuppressive therapy, symptom management, and potential hematopoietic stem cell transplantation. Research continues to explore treatment innovations and earlier diagnosis.… Read More Decoding IPEX Syndrome: From FOXP3 Mutation to Immunodysregulation

Why Do We Die of Cancer? A Brief Overview of the Pathophysiology of Cancer

This article was published on Arbona Health Hub Volume 1 Issue 2 (ISSN: 3065-5544). People often talk about cancer and the ruthless, painful, and terrifying disease it can be. With incidences in the USA of 440.5 per 100,000 men and women per year (National Institute of Cancer, 2017-2021). According to the World Health Organization, “in… Read More Why Do We Die of Cancer? A Brief Overview of the Pathophysiology of Cancer

Decoding the Role of RAGE: Unveiling the Receptor for Advanced Glycation End Products

Hello! Welcome back to the AGEs series. This is the second entry for the series. If you missed the first part, I encourage you to go back and read it before going through this second post. If you remember the previous entry, you most likely know about the main character, the Advanced Glycation End Product… Read More Decoding the Role of RAGE: Unveiling the Receptor for Advanced Glycation End Products