Decoding IPEX Syndrome: From FOXP3 Mutation to Immunodysregulation

IPEX syndrome is a rare genetic disorder caused by mutations in the FOXP3 gene, crucial for regulatory T cell function. Symptoms include enteropathy, endocrinopathy, and dermatitis, appearing early in life. Management involves immunosuppressive therapy, symptom management, and potential hematopoietic stem cell transplantation. Research continues to explore treatment innovations and earlier diagnosis.… Read More Decoding IPEX Syndrome: From FOXP3 Mutation to Immunodysregulation

Management and Risk Prevention for Pregnant Women with Congenital Heart Defects

This article was published on Arbona Health Hub Volume 2 Issue 1 (ISSN: 3065-5544). There are many physiologic changes that have an effect on the cardiovascular system during pregnancy such as hemodynamic alterations, hypercoagulability, increased cardiac output and oxygen demand, vasodilation, etc. (Morton, 2021). As cardiovascular disease is one of the main indirect contributors to… Read More Management and Risk Prevention for Pregnant Women with Congenital Heart Defects